Stavudine [Generic Zerit]

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Description

Stavudine is prescribed to treat HIV infection by preventing reverse transcriptase from working properly. This belongs to the class of medications known as nucleoside reverse transcriptase inhibitors (NRTIs). Reverse transcriptase is a part of the human immunodeficiency virus required to infect cells and to make more viruses. Stavudine slows down the destruction of the immune system.

Stavudine does not cure AIDS and does not prevent it from spreading it to others.

What brands of Stavudine 30 mg or 40 mg sold by BudgetGenerics?

We sell Stavir 30 mg and 40 mg which is made by Cipla Ltd same as the famous brand Zerit.

Recommendations for use of Stavudine (Generic Zerit)

Stavudine is a prescription medicine given for the treatment of HIV infection in adults, children, and infants. Stavudine is always used in combination with other HIV medicines. Stavudine helps to decrease the amount of HIV in the body inorder to improve and allow immune system to work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Stavudine belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors (NRTI).

Stavudine is not a cure for HIV infection. To decrease your risk of spreading HIV disease to others, you should continue to take all HIV medications exactly as prescribed by your doctor. Always use an effective barrier method (latex or polyurethane condoms/dental dams) during sexual activity, and never share personal items such as needles/syringes, toothbrushes, and razors, that may have contacted blood or other body fluids. Consult your doctor or pharmacist for more details.

Please NOTE: HIV medicines can't cure HIV/AIDS, but taking a combination of HIV medicines (called an HIV regimen) every day helps people with HIV live longer, healthier lives. HIV medicines also reduce the risk of HIV transmission. If you are taking HIV medicines, including stavudine, don't cut down on, skip, or stop taking them unless your health care provider tells you to.

Dosage and direction of taking Stavudine 30 mg or 40 mg

Read the Medication Guide and the Patient Information Leaflet provided by your pharmacist before you start using stavudine and each time you get a refill. If you have any questions, consult your doctor or pharmacist.

Stavudine (brand name: Zerit) comes in capsule form in the following strengths:
30-mg capsules
40-mg capsules
Take this medication by mouth with or without food, usually every 12 hours or as directed by your doctor.

The dosage is based on your weight, medical condition, and response to treatment.

For the best effect, take this medication at evenly spaced times, usually every 12 hours. To help you remember, take this medication at the same times every day.

Take stavudine with or without food in combination with other HIV medicines.

Avoid drinking alcohol while taking stavudine. Alcohol may increase your risk of pancreatitis (pain and swelling of your pancreas) or liver damage.

It is very important to continue taking this medication (and other HIV medications) exactly as prescribed by your doctor. Do not skip any doses. Refill your medication before you run out.

Missed Dose of Stavudine
If you miss a dose of stavudine, take the missed dose as soon as you remember it. But if it is almost time for your next dose, skip the missed dose and just take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.

Overdose of Stavudine 30 mg or 40 mg
Do not take more or less of this drug than prescribed or stop taking it (or other HIV medicines) even for a short time unless directed to do so by your doctor. Skipping or changing your dose without approval from your doctor may cause the amount of virus to increase, make the infection more difficult to treat (resistant), or worsen side effects. If overdose seek emergency medical treatment or contact the doctor immediately.

Common use Stavudine (Stavir 30 mg | Stavir 40 mg)

Stavudine belongs to a class (group) of HIV drugs called nucleoside reverse transcriptase inhibitors (NRTIs). NRTIs block an HIV enzyme called reverse transcriptase. (An enzyme is a protein that starts or increases the speed of a chemical reaction.) By blocking reverse transcriptase, NRTIs prevent HIV from multiplying and can reduce the amount of HIV in the body.

Precautions of taking Stavudine (Stavir 30 mg | Stavir 40 mg)?

Stavudine must be taken with other medicines that act against the HIV virus. If Stavudine has been started since unable to prevent multiplication of the virus, therefore, along with this you must start another medicine you have not taken before at the same time.

You can still pass on HIV when taking this medicine, so it's important to take precautions to avoid infecting other people through sexual contact or blood transfer. This medicine is not a cure for HIV infection and you may continue to develop infections or other illnesses associated with HIV disease.

You must remain under the care of your doctor while taking Stavudine.
Tell your doctor, if you have:

allergic reactions to stavudine or any other medicines.

liver problems (such as cirrhosis, hepatitis).

problems with your pancreas (such as pancreatitis).

kidney problems.

tingling, persistent numbness, or pain in the hands or feet (peripheral neuropathy).

gallstones, diabetes or any other medical conditions.

alcoholic beverages. Avoid alcoholic beverages as they may increase your risk for liver problems and/or pancreatitis.

If you are using hormone-based birth control (such as pills, implants, or vaginal rings). For more information about using birth control and HIV medicines at the same time.

If you are pregnant or plan to become pregnant. Whether stavudine can harm an unborn baby is unknown. The combination of stavudine and didanosine (another HIV medicine) should be used with caution during pregnancy and is recommended only if the potential benefit clearly outweighs the potential risk. Tell your healthcare provider right away if you become pregnant while taking stavudine. Discuss with your doctor the risks and benefits of continue stavudine while you are pregnant. If you are breastfeeding or plan to breastfeed. Do not breastfeed if you have HIV or are taking stavudine.

About other prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Especially tell your doctor if you take any of the following medicines: zidovudine, didanosine, doxorubicin, ribavirin, interferon, or hydroxyurea. Stavudine may affect the way other medicines or products work, and other medicines or products may affect how stavudine works. Taking stavudine together with certain medicines or products may cause serious, life-threatening side effects.

Side Effects of taking Stavudine?

Headache or diarrhea may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Your doctor prescribed this medicine after carefully analyzing the benefits over the risks involved. Most people do not experience any serious side effects. Other possible side effects of stavudine include:

Neurologic symptoms (signs that stavudine may be affecting the nerves). Tell your health care provider right away if you have any numbness or tingling in your hands or feet or weakness in your arms, legs, hands, or feet. It may be difficult to recognize neurologic symptoms in children who take stavudine. Ask your child's healthcare provider for the signs and symptoms of this side effect in children.

Changes in body fat (such as increased fat in the upper back and stomach areas, decreased fat in the arms and legs) may occur while you are taking HIV medication. The cause and long-term effects of these changes are unknown. Discuss the risks and benefits of therapy with your doctor, as well as the possible role of exercise to reduce this side effect.

Changes in your immune system (called immune reconstitution inflammatory syndrome or IRIS). IRIS is a condition that sometimes occurs when the immune system begins to recover after treatment with an HIV medicine. As the immune system gets stronger, it may have an increased response to a previously hidden infection. Get medical help right away if you have any serious symptoms, including: headaches that are severe or don't go away, joint pain, numbness/tingling of the hands/feet/arms/legs, vision changes, signs of infection (such as fever, chills, swollen lymph nodes, trouble breathing, cough, non-healing skin sores), signs of an overactive thyroid (such as irritability, nervousness, heat intolerance, fast/pounding/irregular heartbeat, bulging eyes, unusual growth in the neck/thyroid known as a goiter), signs of a certain nerve problem known as Guillain-Barre syndrome (such as trouble breathing/swallowing/moving your eyes, drooping face, paralysis, trouble speaking).

Tell your health care provider if you have any side effect that bothers you or that does not go away.

Drug interaction of taking Stavudine?

Inform your doctor about any medications that you are taking including prescription medications, over the counter medications, vitamins, supplements and herbal remedies. Do not start, stop and change the dosage of any medicine without your doctor's permission.

Stavudine may make you dizzy. Consumption of alcohol or marijuana can increase the risk of drowsiness. Do not operate machinery, drive a car or do anything that require alertness until you can do it safely. Understand how this medication affects you.

IMPORTANT: Inform the doctor, if you are currently taking any of the following medicines:

doxorubicin

orlistat

didanosine

hydroxyurea

zidovudine

zidovudine/Ribavirin (tribavirin)

vincristine

isoniazid

If you are taking any of these medicines, tell your doctor immediately. Taking these medicines with Stavudine could create the potential for serious and/or life-threatening side-effects or stop Stavudine from working properly.

Storage of Stavudine 30 mg or 40 mg?

Keep this medicine out of the sight and reach of children.
Store at 15°C - 30°C (59°F - 77°F); protect drug from excessive light, humidity, and temperature over 30°C (86°F)
Keep stavudine capsules in the container that they came in and keep the container tightly closed.
Throw away capsules that are no longer needed or expired (out of date).
Medicines should not be disposed of via waste water or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help to protect the environment.
Stavudine 30 mg or 40 mg should not be used after the given expiration date.